Publications

Fenner K, Zahn D, Jöhncke U, Sigmund G, Mayer P, Hughes C, Arp HPH, Davenport RJ, Kapanen A, Reemtsma T, 2026. Persistence Assessment of Chemicals: Trajectories toward New Approach Methodologies (P-NAMs). Environmental Science & Technology 60, 15, 11243–11252.

Schofield K, Hughes CB, Scheerbaum D, Maeß C, Brown DM, Hakvåg S, 2025. The selection of reference substances for improving chemical persistence assessment in higher tier OECD 309 simulation tests. Ecotoxicology and Environmental Safety 308, 119499.

Hughes CB, Griffiths M, Cook S, van de Meent D, Parsons J, Lyon D, Ott A, 2025. Developing a weight-of-evidence methodology for persistence assessment of substances in the environment. Integrated Environmental Assessment and Management, vjaf139.

ECETOC, 2025. Overcoming challenges and advancing (bio)degradation guidelines: OECD TG309 revisited.Workshop Report no.41. European Centre for Ecotoxicology and Toxicology of Chemicals.

Swansborough C, Soto J, Shapland I, Hughes CB, Jennings E, McArdle M, Mihaich E, Majoris E, Bunge M, 2025. Trend analysis of environmental concentrations of Bisphenol A in European waters and sediments. Environmental Research, 121946.

Whelan MJ, Pemberton E, Hughes CB, Swansborough C, Goslan EH, Gouin T, Bell VA, Bird E, Bull S, Segal L, Cook SH, Jephcote C, Fane S, 2025. A tiered assessment of human health risks associated with exposure to persistent, mobile and toxic chemicals via drinking water. Science of the Total Environment 958, 177868.

Davis C, Brown D, Swansborough C, Hughes C, Saunders L, Camenzuli L, Lyon D, 2024. Predicting hydrocarbon primary biodegradation in soil & sediment systems using system parameterization & machine learning. Environ Toxicol Chem 43: 1352-1363.

Martin-Aparicio A, Camenzuli L, Hughes C, Pemberton E, Saunders D, Wang N, Lyon DY, 2023. Are ready biodegradation tests effective screens for non-persistence in all environmental compartments? Environmental Sciences Europe 35, 67.

Shrestha P, Hughes CB, Camenzuli L, Lyon D, Meisterjahn B, Hennecke T, Griffiths M, Hennecke D, 2023. Improved closed test setup for biodegradation testing of slightly volatile substances in water-sediment systems (OECD 308). Chemosphere 324, 138294.

Hughes CB, Griffiths M, Swansborough C, 2022. Framework to Improve the Use of Weight of Evidence in Persistence Assessments - Cefic-LRI ECO52 project. Report for the European Chemicals Industry Council (Cefic). Ricardo Energy & Environment.

Hughes CB, Griffiths M, Brown D, 2022. Guidance for the Persistence Assessment of Difficult Test Substances - Cefic-LRI ECO52 project. Report for the European Chemicals Industry Council (Cefic). Ricardo Energy & Environment.

Hughes CB, Griffiths M, Pemberton E, 2022.Guidance for the Persistence Assessment of UVCB Substances - Cefic-LRI ECO52 project. Report for the European Chemicals Industry Council (Cefic). Ricardo Energy & Environment.

Johansen B, Louro B, Kukla I, Pattle G, Denmark J, Hughes C, Jeronimo-Roque D, 2021. Economic Analysis of the Impacts of the Chemicals Strategy for Sustainability - Phase 1 Report. Report for the European Chemicals Industry Council (Cefic). Ricardo Energy & Environment.

Hughes CB, Brown DM, Camenzuli L, Redman AD, Arey JS, Vione D, Wang N, Vaiopoulou E, 2020. Can a chemical be both readily biodegradable AND very persistent (vP)? Weight-of-evidence determination demonstrates that phenanthrene is not persistent in the environment. Environmental Sciences Europe 32, 148.

Brown DM, Camenzuli L, Redman AD, Hughes C, Wang N, Vaiopoulou E, Saunders D, Villalobos A, Linington S, 2020. Is the Arrhenius-correction of biodegradation rates, as recommended through REACH guidance, fit for environmentally relevant conditions? An example from petroleum biodegradation in environmental systems. Science of the Total Environment 732, 139293.

Brown DM, Lyon D, Saunders DMV, Hughes CB, Wheeler JR, Shen H, Whale G, 2020. Biodegradability assessment of complex, hydrophobic substances: Insights from gas-to-liquid (GTL) fuel and solvent testing. Science of the Total Environment 727, 138528.

Boegi C, Claessens M, Hughes C, Lampi M, Mandrillon AL, Redman A, 2020. Sufficiency of aquatic hazard data for environmental risk assessment in sediment and soil. Technical Report No 134. European Centre for Ecotoxicology and Toxicology of Chemicals.

Eadsforth CV, Hughes CB, Redman AD, Vaiopoulou E, 2020. Aquatic toxicity of petroleum substances: Extending the validation of the biomimetic extraction (BE) method for use in hazard assessments. Concawe. Report no. 3/20.

Shrestha S, Meisterjahn B, Hughes CB, Mayer P, Birch H, Hennecke D, 2020. Biodegradation testing of volatile hydrophobic chemicals in water-sediment systems – Experimental developments and challenges. Chemosphere 238, 124516.

Kutsarova S, Yordanova D, Karakolev Y, Stoeva S, Comber M, Hughes C, Vaiopoulou E, Dimitrov S, Mekenyan O, 2019. UVCB substances II: Development of an endpoint non-specific procedure for selection of computationally generated representative constituents. Environmental Toxicology and Chemistry 38, 682-694.

Shrestha S, Meisterjahn B, Klein M, Mayer P, Birch H, Hughes C, Hennecke D, 2019. Biodegradation of volatile chemicals in soil – Separating volatilization and degradation in improved test setup (OECD 307). Environmental Science & Technology 53, 20-28.

Gouin T, Salinas E, Coady K, Franco A, Hoke R, Hughes C, Léonard M, Lyon D, Sergent JA, 2018. An evaluation of the challenges and limitations associated with aquatic toxicity and bioaccumulation studies for sparingly soluble and manufactured particulate substances. Technical Report No 132. European Centre for Ecotoxicology and Toxicology of Chemicals.

Brown DM, Hughes CB, Spence M, Bonte M, Whale G, 2018. Assessing the suitability of a manometric test system for determining the biodegradability of volatile hydrocarbons. Chemosphere 195, 381-389.

Whale GF, Dawick J, Hughes CB, Lyon D, Boogaard PJ, 2018. Toxicological and Ecotoxicological Properties of Gas-to-Liquid (GTL) Products. 2. Ecotoxicology. Critical Reviews in Toxicology 48, 273-296.